When you run the Debugger against mappings with sequence generators and mapping variables, the Integration Service might save or discard persisted values:
Discard persisted values.
The Integration Service does not save final values of generated sequence numbers or mapping variables to the repository when you run a debug session or you run a session in debug mode and discard target data.
Save persisted values.
The Integration Service saves final values of generated sequence numbers and mapping variables to the repository when you run a session in debug mode and do not discard target data. You can view the final value for Sequence Generator and Normalizer transformations in the transformation properties.