Every partner must have a Partner definition within the Informatica B2B Data Exchange. Therefore define a profile within the Informatica B2B Data exchange for each partner. Fill in the ISA06 - Interchange sender id parameter value.
As soon as connection is established and the file arrives at the VAN file receive endpoint, the file will be consumed by the DX server, and routed to the matching partner. An event will be created which can be seen on the DX console 'Event List'.